THPTA

Catalog#
Unit Size
Price (USD)
Availability
Qty
1010-100
100 mg
$55.00
In stock
1010-500
500 mg
$239.00
In stock
1010-1000
1000 mg
$395.00
In stock
1010-5G
5 g
$1,650.00
In stock

    THPTA (tris-hydroxypropyltriazolylmethylamine) is a water-soluble, very effective accelerating ligand for copper-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). In addition to greatly enhancing the rate of CuAAC, THPTA minimizes perturbations to the physiological state of the cells or organisms probed and allows for the effective bioconjugation with suppressed cell cytotoxicity by further lowering Cu loading in the catalyst formulation. The water-soluble THPTA ligand further simplifies click chemistry by allowing the entire reaction to be run in water.

    Molecular weight
    434.50
    Chemical composition
    C18H30N10O3
    CAS
    760952-88-3
    Solubility
    Water, DMSO, DMF, MeOH
    Purity
    >95% (HPLC)
    Appearance
    Off-white to grey solid
    Storage conditions
    4°C.
    Shipping conditions
    Ambient temperature

    1. Tong, M., et al. (2020). Effective Method for Accurate and Sensitive Quantitation of Rapid Changes of Newly Synthesized Proteins. Anal. Chem., 92(14), 10048-57. [PubMed]
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