Tetrazine-PEG5-NHS Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
1143-10
10 mg
$149.00
In stock
1143-1
4 x 2 mg
$149.00
In stock
1143-25
25 mg
$235.00
In stock
1143-100
100 mg
$695.00
In stock

    Tetrazine-PEG5-NHS Ester is an amine-reactive labeling reagent often used for modification of proteins, peptides, or amine-modified oligonucleotides with tetrazine moiety. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics, generally at least 10 fold faster compared to methyl substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG5) spacer arm.

    Molecular weight
    604.61
    Chemical composition
    C27H36N9O10
    CAS
    1682653-80-0
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    Red amorphous solid to red oil
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Ambient temperature

    1. Ingham, E. S., et al. (2020). Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation. Nat Commun, 11, 2102. [Nature Communications]
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