TCO-PEG4-NHS Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
A137-2
4 x 2 mg
$149.00
In stock
A137-10
10 mg
$139.00
In stock
A137-25
25 mg
$235.00
In stock
A137-100
100 mg
$575.00
In stock

    TCO-PEG4-NHS Ester is a pegylated lebeling reagent with enhanced solubility in aqueous buffers used for TCO labeling of antibodies, proteins and other primary amine-containing macromolecules. A long, hydrophilic PEG4 spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary tetrazine-containing molecules.

    Molecular weight
    514.57
    Chemical composition
    C24H38N2O10
    CAS
    1621096-79-4
    Solubility
    DMSO, DMF, THF, Acetonitrile, Dichloromethane
    Purity
    >95% (HPLC)
    Appearance
    Colorless to slightly yellow oil
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Dry ice

    1. Ingham, E. S., et al. (2020). Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation. Nat Commun, 11, 2102. [Nature Communications]
    2. Sun, N., et al. (2020). Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring. Nat Commun., 11, 4489. [PubMed]
    3. Allo, B., et al. (2018). Clickable and High-Sensitivity Metal-Containing Tags for Mass Cytometry. Bioconjugate Chem. , 29(6), 2028-38. [PubMed]
    Related Products
    TCO-PEG4-TFP Ester

    An amine-reactive reagents with enhanced labeling efficiency.