An amine-reactive, non-activated building block with enhanced solubility in aqueous media used for derivatizing amine-containing molecule in the presence of activators (e.g. EDC, or HATU) through a stable amide bond.
- Marquard, A.N., et al. (2020). Expanding the Scope of Antibody Rebridging with New Pyridazinedione-TCO Constructs. Bioconjug Chem., 31(6), 1616-23. [PubMed]
An amine-reactive labeling reagents with enhanced solubility in aqueous buffers.