TCO-PEG3-Maleimide

Catalog#
Unit Size
Price (USD)
Availability
Qty
1002-1
4 x 2 mg
$169.00
In stock
1002-10
10 mg
$115.00
In stock
1002-25
25 mg
$215.00
In stock
1002-100
100 mg
$615.00
In stock

    TCO-PEG3-Maleimide enables simple and efficient incorporation of TCO moiety onto antibodies, cysteine-containing peptides and other thiol-containing molecules. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bonds. The hydrophilic polyethylene glycol (PEG) spacer arm improves solubility in aqueous buffers.

    Molecular weight
    523.62
    Molecular formula
    C26H41N3O8
    CAS
    1609659-01-9
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    Colorless to slightly yellow oil
    Storage Conditions
    -20°C. Desiccate
    Shipping conditions
    Overnight, dry ice

    1. Allo, B., et al. (2018). Clickable and High-Sensitivity Metal-Containing Tags for Mass Cytometry. Bioconjugate Chem. , 29(6), 2028-38. [PubMed]