TBTA

Catalog#
Unit Size
Price (USD)
Availability
Qty
1061-100
100 mg
$49.00
In stock
1061-500
500 mg
$85.00
In stock
1061-1G
1 g
$120.00
In stock

    TBTA was introduced shortly after the copper-catalyzed azide-alkyne cycloaddition reaction was discovered to mitigate thermodynamic instability of Cu(I) in aerobic media. TBTA is a water-insoluble ligand and must be first dissolved in DMSO or DMF.

    Molecular weight
    530.62
    Chemical composition
    C30H30N10
    CAS
    510758-28-8
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    Off-white to grey solid
    Storage conditions
    4°C.
    Shipping conditions
    Ambient temperature

    1. Gray, R. A. V., et al. (2021). Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry. JoVE Journal, 10 (3791), 62107. [JoVE Journal]
    2. Pratt Matthew R., et al. (2020). Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins. Frontiers in Chemistry, 8, 318. [Frontiers in Chemistry]
    3. White, F. K. H., et al. (2019). S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane. J Biol Chem., 294 (36), 13487-13501. [PubMed]
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