PC Biotin-NHS ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
1225-10
10 mg
$149.00
In stock
1225-1
4 x 1 mg
$149.00
In stock
1225-25
25 mg
$245.00
In stock
1225-100
100 mg
$695.00
In stock

PC Biotin-NHS Ester as a unique amine reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin beads. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

Molecular weight
840.89
Chemical composition
C36H52N6O15S
CAS
N/A
Solubility
DMSO, DMF, DCM, THF, Chloroform
Purity
>95%
Appearance
Slightly yellow amorphos solid to oil
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature