N-(4-pentynoyl)-galactosamine tetraacylated (Ac4GalNAl)

Catalog#
Unit Size
Price (USD)
Availability
Qty
1156-5
5 mg
$149.00
In stock
1156-25
25 mg
$255.00
In stock
1156-100
100 mg
$635.00
In stock

    Ac4GalNAl is an unnatural alkyne-containing monosaccharide building block. The alkyne moiety can be used for modification though chemoselective ligation chemistries including CuAAC or various Pd-catalyzed coupling reactions. The acetyl groups increase solubility in many solvents and make handling of this building easier.

    Molecular weight
    427.40
    Chemical composition
    C19H25NO10
    CAS
    1658458-26-4
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >90%
    Appearance
    White to grey amorphous solid
    Storage conditions
    -20°C.
    Shipping conditions
    Ambient temperature

    1. Wood, T. M., et al. (2021). Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase. ACS Chem. Biol., [PubMed]
    2. Daughtry, J. L., et al. (2020). Clickable Galactose Analogues for Imaging Glycans in Developing Zebrafish. ACS Chem Biol., 15 (2), 318-324. [PubMed]
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