Mono-sulfone Acid

Catalog#
Unit Size
Price (USD)
Availability
Qty
1506-1000
1000 mg
$395.00
In stock
1506-5G
5 g
$1,295.00
In stock

    Mono-sulfone is a thiol-specific labeling reagent that undergo alkylation to generate a thio-ether bond between the protein and mono-sulfone activated reagent. Once mono-sulfone reagent is conjugated to a protein or peptide, exchange reactions leading to deconjugation can be easily avoided by treating the conjugate with a mild reducing agent in a way analogous to the process used for conjugation reactions involving reductive amination.

    Molecular weight
    332.37
    Chemical composition
    C17H16O5S
    CAS
    n/a
    Solubility
    DMSO, DMF
    Purity
    >95% (HPLC)
    Appearance
    Grey solid
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Ambient temperature

    1. Badescu, G., et al. (2014). A New Reagent for Stable Thiol-Specific Conjugation. Bioconjug. Chem., 25(3), 460-9. [PubMed]