Methyltetrazine-PEG4-NHS Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
1069-1
4 x 2 mg
$149.00
In stock
1069-10
10 mg
$149.00
In stock
1069-25
25 mg
$278.00
In stock
1069-100
100 mg
$630.00
In stock
1069-500
500 mg
$1,295.00
In stock
1069-1000
1000 mg
$1,950.00
In stock

    Methyltetrazine-PEG4-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. The PEG spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary TCO-containing molecules. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.

    Molecular weight
    533.53
    Chemical composition
    C24H31N5O9
    CAS
    1802907-92-1
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    Red crystalline
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Ambient temperature

    1. Marquard, A.N., et al. (2020). Expanding the Scope of Antibody Rebridging with New Pyridazinedione-TCO Constructs. Bioconjug Chem., 31(6), 1616-23. [PubMed]
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