Methyltetrazine-PEG4-Acid

Catalog#
Unit Size
Price (USD)
Availability
Qty
1073-25
25 mg
$95.00
In stock
1073-100
100 mg
$395.00
In stock
1073-500
500 mg
$895.00
In stock
1073-1000
1000 mg
$1,495.00
In stock

Methyltetrazine-PEG4-Acid is one of the most stable tetrazines commercially available. In addition to stabilization provided by the electron donating methyl group, the electron donating alkoxy substituent on the aromatic ring further improves the stability of Methyltetrazine-PEG4-Acid. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.

Molecular weight
436.56
Chemical composition
C20H28N4O7
CAS
1802907-91-0
Solubility
DMSO, DMF, DCM, THF, Chloroform
Purity
>95% (HPLC)
Appearance
Red crystalline
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature

Methyltetrazine-PEG4-Acid is one of the most stable tetrazines commercially available. In addition to stabilization provided by the electron donating methyl group, the electron donating alkoxy substituent on the aromatic ring further improves the stability of Methyltetrazine-PEG4-Acid. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.

Methyltetrazine-PEG4-Acid is an amine-reactive, non-activated, building block often used for modification of primary or secondary amines in the presence of activators (e.g. EDDC, HATU, or TSTU). It is also often used for preparation of custom activated ester such as sulfo-NHS ester, sulfo-tetrafluophenol (STP).

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