MB 594 DBCO

Catalog#
Unit Size
Price (USD)
Availability
Qty
1184-1
1 mg
$149.00
In stock
1184-5
5 mg
$455.00
In stock
1184-25
25 mg
$1,395.00
In stock

MB™ 594 is a bright, red fluorescent probe with absorption and emission maxima similar to Texas Red dye or Alexa Fluor® 594. The dye is based on a novel class of rhodamine dyes. Unlike traditional rhodamine dyes, MB™ 594 is not only bright and photostable but also highly water-soluble and pH-insensitive. MB™ 594 can be used as a high performance replacement for Alexa Fluor® 594, DyLight® 594, and Texas Red.

Abs/Em Maxima
601/623 nm
Extinction Coefficient
110,000
Flow Cytometry Laser Line
532 or 594 nm
Microscopy Laser Line
594 nm
Spectrally Similar Dyes
Alexa Fluor® 594, Atto™ 594, CF® 594 Dye, DyLight® 594
Molecular weight
1102.26
CAS
N/A
Solubility
Water, DMSO, DMF, MeOH
Purity
>95% (HPLC)
Appearance
Blue solid
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature

MB™ 594 is a bright, red fluorescent probe with absorption and emission maxima similar to Texas Red dye or Alexa Fluor 594®. The dye is based on a novel class of rhodamine dyes. Unlike traditional rhodamine dyes, MB™ 594 is not only bright and photostable but also highly water-soluble and pH-insensitive. MB™ 594 can be used as a replacement for Alexa Fluor 594, DyLight 594, and Texas Red.

MB™ 594 DBCO dye reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. In application where the presence of copper is a concern MB™ 594 DBCO is an ideal alternative to copper requiring fluorescent alkynes.

MB™ 594 DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.

DBCO reagents are the most commonly used substrates for strain-promoted copper-free azide-alkyne click chemistry reactions. DBCO compounds react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

MB594

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