IsoTaG Biotin Azide Pack
IsoTaG Biotin Azide probes take advantage of the mass shift of stable heavy isotope labels (SHLs) to enable mass-independent chemical proteomics platform that helps to address unique challenges of the proteome characterization. In this approach a unique isotopic signature is embedded exclusively into the peptides and it serves as a computationally recognizable full-scan MS reporter. A computational algorithm, termed isotopic signature transfer and mass pattern prediction (IsoStamp), for the detection of recoded species in full-scan mass spectra, was also developed by the Carolyn Bertozzi group. IsoTaG H/L Biotin Azide pack contains 2 mg of light [M] and heave [M+2] probe encoded by 2 C12 or 2 C13 atoms.
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