Dde Biotin Picolyl Azide
Catalog#
Unit Size
Price (USD)
Availability
Qty
1186-1
1 mg
$95.00
In stock
1186-5
5 mg
$279.00
In stock
1186-25
25 mg
$735.00
In stock
Dde Biotin Picolyl Azide is an azide-activated cleavable biotin probe that allows for efficient recovery of avidin-bound protein complexes in affinity-based assays. This reagent contains a biotin moiety linked to azide group through a spacer arm containing a hydrazine-cleavable Dde moiety. Under mild conditions (2% aqueous hydrazine), the Dde liner is cleaved, releasing the biotin tag and any avidin conjugate bound to it.
Learn more about picolyl azide reagents.Molecular weight
815.98
Molecular weight left behind
220.24
Chemical composition
C38H57N9O9S
CAS
2055048-42-3
Solubility
DMSO, DMF, THF, DCM, Chloroform
Appearance
Oil to amorphous solid
Storage conditions
-20°C.
Shipping conditions
Ambient temperature
- Howell, A. R., et al. (2021). α-Methylene-β-Lactone Scaffold for Developing Chemical Probes at the Two Ends of the Selectivity Spectrum. Chembiochem., 22 (3), 505-515. [PubMed]
- Matthew E. G., et al. (2017). Comprehensive Mapping of O-GlcNAc Modification Sites Using a Chemically Cleavable Tag. Mol. Biosyst, 12: 1756–59. [PubMed]
- Gertsik N., et al. (2017). Mapping the Binding Site of BMS-708163 on y-Secretase with Cleavable Photoprobes. Cell Chemical Biology, 32: 3-8. [PubMed]
- Jiang, H., et al. (2014). Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chem., 25: 698-706. [PubMed]
- Yang Y., et al. (2013). Cleavable Trifunctional Biotin Reagents for Protein Labeling, Capture, and Release. Chem. Commun., 48: 5366-86. [PubMed]
- Uttamapinant, C., et al. (2012). Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling. Angew. Chem. Int. Ed,. 51: 5852–56. [PubMed]
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