Dde Biotin-Azide

Catalog # Pkg Size Price(USD) Quantity
1136-10 10 mg $179.00
1136-25 25 mg $329.00
1136-100 100 mg $1,095.00

Extraordinary strength of the streptavidin-biotin interaction allows for efficient capturing of even highly dilute targets; however, it makes recovery of proteins from affinity resins challenging. Dde biotin probes eliminate a major limitation of the streptavidin-biotin affinity purification associated with extraordinary strength of the streptavidin-biotin interaction. This reagent contains a biotin moiety linked to an azide moiety through a spacer arm containing a Dde linker. Captured biomolecules can be efficiently released, typically >90%.



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3. Gertsik N., et al. (2017). Mapping the Binding Site of BMS-708163 on y-Secretase with Cleavable Photoprobes. Cell Chemical Biology, 32: 3-8.