DBCO-Sulfo-NHS Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
A124-10
10 mg
$95.00
In stock
A124-25
25 mg
$195.00
In stock
A124-100
100 mg
$495.00
In stock
A124-500
500 mg
$1,695.00
In stock

DBCO-Sulfo-NHS Ester is water-soluble reagent that enables simple and efficient labeling of antibodies, proteins and any other primary amine-containing macromolecules with DBCO moiety in 100% aqueous buffers. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds.

Molecular weight
532.50
Chemical composition
C25H21N2NaO8S
CAS
1400191-52-7
Solubility
Water, DMSO, DMF
Purity
>95% (HPLC)
Appearance
White to slightly grey crystalline
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature

DBCO-Sulfo-NHS Ester Ester is water-soluble reagent that enables simple and efficient labeling of antibodies, proteins and any other primary amine-containing macromolecules with DBCO moiety in 100% aqueous buffers. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. DBCO-Sulfo-NHS Ester is a reagent of choice for applications that cannot tolerate organic co-solvents or are complicated by their inclusion. Specific labeling of cell surface proteins is another common application for these uniquely water-soluble and membrane impermeable reagents.

DBCO reagents, also known as ADIBO or DIBAC, are the most commonly used substrates for strain-promoted click chemistry reaction. DBCO compounds react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Enter only one — either volume or amount of protein to be labeled
Enter only one — either maximum concentration of DMSO or volume DMSO added to label
Related Products
DBCO-PEG5-TFP Ester

An amine-reactive reagents with enhanced labeling efficiency.

Sulfo DBCO-TFP Ester

A water-soluble activated ester for modification of primary amine-containing molecules with sulfo DBCO moiety.

DBCO-STP Ester

A water-soluble labeling reagent with improved labeling efficiency.