DBCO-PEG5-NHS Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
A102P-2
4 x 2 mg
$165.00
In stock
A102P-10
10 mg
$125.00
In stock
A102P-25
25 mg
$235.00
In stock
A102P-100
100 mg
$495.00
In stock
A102P-500
500 mg
$1,520.00
In stock

    DBCO-PEG5-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the labeled molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary azide-containing molecules.

    Molecular weight
    693.74
    Chemical composition
    C36H43N3O11
    CAS
    1378531-80-6
    Solubility
    DMF, DMSO, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    Viscous oil or amorphous solid
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Ambient temperature

    1. Tracy, C. M., et al. (2019). Cysteine-Directed Bioconjugation of a Platinum(II)-Acridine Anticancer Agent. Inorg Chem., 58 (1), 43-46. [PubMed]
    2. Allo, B., et al. (2018). Clickable and High-Sensitivity Metal-Containing Tags for Mass Cytometry. Bioconjugate Chem. , 29(6), 2028-38. [PubMed]
    3. Nedrow-Byerst, J.R., et al. (2013). PSMA-targeted SPECT agents: mode of binding effect on in vitro performance. Prostate., 73(4), 355-62-9. [PubMed]
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