DBCO-PEG5-Acid is an amine-reactive, non-activated building block with enhanced solubility in aqueous media used for derivatizing amine-containing molecule in the presence of activators (e.g. EDC, or HATU) through a stable amide bond.
DBCO reagents are the most commonly used substrates for strain-promoted click reactions. DBCO compounds react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
DMSO, DMF, DCM, THF, Chloroform
Yellow to slightly orange oil
TCO-PNB Ester (equatorial) - 25 mg
An amine-reactive, cyclooctene-containing building block.