DBCO-PEG4-Maleimide
Catalog#
Unit Size
Price (USD)
Availability
Qty
A108P-10
10 mg
$139.00
In stock
A108P-25
25 mg
$235.00
In stock
A108P-100
100 mg
$575.00
In stock
A108P-500
500 mg
$1,850.00
In stock
DBCO-PEG4-Maleimide enables simple and efficient incorporation of DBCO moiety onto antibodies, cysteine-containing peptides and other thiol-containing molecules. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bonds. The hydrophilic polyethylene glycol (PEG) spacer arm improves solubility in aqueous buffers.
Molecular weight
674.74
Chemical composition
C36H42N4O9
CAS
1480516-75-3
Solubility
DMSO, DMF, THF, Acetonitrile, Dichloromethane
Purity
>95% (HPLC)
Appearance
Yellow to slightly orange oil
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature
- Esser-Kahn, A. P., et al. (2020). Pathogen-like Nanoassemblies of Covalently Linked TLR Agonists Enhance CD8 and NK Cell-Mediated Antitumor Immunity. ACS Cent. Sci., 10, 1021. [ACS Publications]
- Kiseleva, R., et al. (2020). MBivalent engagement of endothelial surface antigens is critical to prolonged surface targeting and protein delivery in vivo. FASEB Jornal, 34, 9, 11577-93. [FASEB]
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