Biotin-PEG4-DBCO

Catalog#
Unit Size
Price (USD)
Availability
Qty
A105-5
5 mg
$89.00
In stock
A105-25
25 mg
$330.00
In stock
A105-100
100 mg
$830.00
In stock

    A biotin probe for copper-free click chemistry reaction, Biotin-PEG4-DBCO reacts with azides to form a stable triazole and does not require Cu-catalyst or elevated temperatures. Often a reagent of choice in live cell surface glycans and lipids studies where the presence of cytotoxic copper catalyst is not acceptable. In application where the presence of copper is a concern Biotin-PEG4-DBCO is an ideal alternative to copper requiring biotin-alkynes.

    Molecular weight
    749.92
    Chemical composition
    C39H51N5O8S
    CAS
    1255942-07-4
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    White to grey amorphous solid
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Ambient temperature

    1. Bierbach, U., et al. (2021). DNA Adduct Detection after Post-Labeling Technique with PCR Amplification (DNA-ADAPT-qPCR) Identifies the Pre-ribosomal RNA Gene as a Direct Target of Platinum-Acridine Anticancer Agents. Chemistry., 27 (59), 14681-14689. [PubMed]
    2. Pratt Matthew R., et al. (2020). Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins. Frontiers in Chemistry, 8, 318. [Frontiers in Chemistry]
    3. Bernardim, B., et al. (2020). Precise Installation of Diazo-Tagged Side-Chains on Proteins to Enable In Vitro and In-Cell Site-Specific Labeling Bioconjugate Chem., 31 (6), 1604-10. [PubMed]
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