DBCO-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. Short spacer arm adds minimal mass to modified molecules (228.3 daltons).
This product is not recommended for labeling of proteins or any other biopolymers in aqueous buffers due to poor aqueous solubility.
|Solubility||DMSO, DMF, DCM, THF, Chloroform|
|Appearance||White to slightly grey crystalline|
|Shipping conditions||Ambient temperature|
|DBCO-Sulfo-NHS Ester||A water-soluble reagent for labeling antibodies, proteins.|
|DBCO-PEG5-NHS ester||An amine-reactive labeling reagent with enhanced water stability and solubility.|
|Sulfo DBCO-NHS Ester||A water-soluble, amine reactive reagent with hydrophilic sulfonated spacer arm.|
|DBCO-PEG13-NHS Ester||An amine-reactive labeling reagent with hydrophilic PEG13 spacer arm.|