DBCO-C6-NHS Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
A102-100
100 mg
$255.00
In stock
A102-1000
1000 mg
$1,175.00
In stock
A102-5G
5 g
$3,920.00
In stock

    DBCO-C6-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media. The extended 6-carbon atom spacer arm drastically improves solubility of this reagent in commonly used organic solvents such as dichloromethane, chloroform, THF, and ethyl acetate. In addition extended spacer arm significantly improves derivatization efficiency and stability of conjugates.

    This product is not recommended for labeling of proteins or any other biopolymers in aqueous buffers due to poor aqueous solubility.

    Molecular weight
    430.45
    Chemical composition
    C25H22N2O5
    CAS
    1384870-47-6
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    White to slightly grey crystalline
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Ambient temperature

    1. Wiener, J., et al. (2020). Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics. Sci Rep., 10 (1), 1457. [PubMed]
    2. Saikatr, M., et al. (2015). A Three-Arm Scaffold Carrying Affinity Molecules for Multiplex Recognition Imaging by Atomic Force Microscopy: The Synthesis, Attachment to Silicon Tips, and Detection of Proteins J. Am. Chem. Soc., 137(23), 7415-25. [PubMed]
    Related Products
    Sulfo DBCO-TFP Ester

    A water-soluble activated ester for modification of primary amine-containing molecules with sulfo DBCO moiety.

    6-Azidohexanoic Acid STP Ester

    A water-soluble labeling reagent with improved labeling efficiency.

    DBCO-STP Ester

    A water-soluble labeling reagent with improved labeling efficiency.

    DBCO-PEG5-TFP Ester

    An amine-reactive reagents with enhanced labeling efficiency.