DBCO-C6-Acid

Catalog#
Unit Size
Price (USD)
Availability
Qty
A101-100
100 mg
$195.00
In stock
A101-1000
1000 mg
$1,150.00
In stock
A101-5G
5 g
$3,750.00
In stock

DBCO-C6-Acid, also known as ADIBO or DIBAC is a non-activated building block routinely used for synthesis of complex molecules to be used in Cu-free ligation applications. Primary or secondary amines can be efficiently functionalized with DBCO moiety in the presence of activators (e.g. EDC, or HATU) through a stable amide bond.

The extended 6-carbon long spacer arm improves solubility of this reagent in commonly used organic solvents such as dichloromethane, chloroform, THF, and ethyl acetate. In addition, extended spacer arm significantly improves coupling efficiency and stability of conjugates.

Molecular weight
333.83
Chemical composition
C21H19NO3
CAS
1425485-72-8
Solubility
DMSO, DMF, DCM, THF, Chloroform
Purity
>95% (HPLC)
Appearance
Slightly grey to slightly orange solid
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature

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