Methyltetrazine-activated Cy7 dye that reacts with TCO-containing compounds via a Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1 s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
|Spectrally similar dyes||Alexa Fluor® 750,RDye® 750RD, CF™ 750 Dye, DyLight™ 750|
|Solubility||Water, DMSO, DMF, MeOH|
|Appearance||Dark green solid|
|Shipping conditions||Ambient temperature|