Cy3 Methyltetrazine

Catalog#
Unit Size
Price (USD)
Availability
Qty
1018-1
1 mg
$120.00
In stock
1018-5
5 mg
$329.00
In stock
1018-25
25 mg
$1,395.00
In stock

Methyltetrazine-activated Cy3 probe that reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 M-1 -1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.

Abs/Em Maxima
550/570 nm
Extinction Coefficient
150,000
Flow Cytometry Laser Line
532 or 555 nm
Microscopy Laser Line
532 or 555 nm
Spectrally Similar Dyes
Alexa Fluor® 555, Atto™ 555, CF™ 555 Dye, DyLight™549
Molecular weight
908.07
CAS
1676067-48-3
Solubility
Water, DMSO, DMF, MeOH
Purity
>95% (HPLC)
Appearance
Red solid
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature

Methyltetrazine-activated Cy3 probe that reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 M-1 -1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date. described to date.

Cy®3 is a bright, water-soluble, and pH insensitive orange-fluorescent dye that can be excited using the 532 nm or 555 nm laser line and visualized with TRITC (tetramethylrhodamine) filter sets. Cy3 conjugates give less background than TAMRA and most other commonly used fluorescent dyes.

Cy®Dye is a trademark of GE Healthcare

Cy3

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