BTTAA

Catalog#
Unit Size
Price (USD)
Availability
Qty
1236-100
100 mg
$129.00
In stock
1236-500
500 mg
$495.00
In stock
1236-1000
1000 mg
$895.00
In stock

BTTAA is a newest generation, water-soluble accelerating ligand for CuAAC that provides much greater rate enhancement compared to previous generation ligands (e.g. THPTA or TBTA). More importantly, it minimizes perturbations to the physiological state of the cells or organisms probed and allows for effective bioconjugation with suppressed cell cytotoxicity by further lowering copper loading in the catalyst formulation.

Molecular weight
430.52
Chemical composition
C19H30N10O2
CAS
1334179-85-9
Solubility
Water, DMSO, DMF, MeOH
Purity
>95% (HPLC)
Appearance
Off-white to grey solid
Storage conditions
4°C.
Shipping conditions
Ambient temperature

1. Besanceney-Webler, C., et al. (2011). Increasing the efficacy of bioorthogonal click reactions for bioconjugation: a comparative study. Angew. Chem. Int. Ed,. 50(35): 8051–6. [PubMed]

2. Jiang, H., et al. (2014). Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chem.,, 25, 698-706. [PubMed]

3. Uttamapinant, C., et al. (2012). Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling. Angew. Chem. Int. Ed,., 51, 5852-56. [PubMed]

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