Biotin Picolyl Azide

Catalog#
Unit Size
Price (USD)
Availability
Qty
1167-5
5 mg
$129.00
In stock
1167-25
25 mg
$295.00
In stock
1167-100
100 mg
$895.00
In stock

Biotin Picolyl Azide is an advanced biotin probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boosted the efficiency of the CuAAC reaction resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides was reported (see Selected References).

Learn more about picolyl azide reagents.

Molecular weight
622.74
Chemical composition
C27H42N8O7S
CAS
N/A
Solubility
DMSO, DMF
Purity
>95% (HPLC)
Appearance
Off-white to slightly orange amorphous solid
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature

1. Jiang, H., et al. (2014). Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chem.,, 25, 698-706. [PubMed]

2. Uttamapinant, C., et al. (2012). Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling. Angew. Chem. Int. Ed,., 51, 5852-56. [PubMed]

3. Gaebler, A.,et al. (2016). A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins. J. Lipid. Res., 57, 1934-47. [PubMed]

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