Biotin-PEG4-STF Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
1404-5
5 mg
$95.00
In stock
1404-25
25 mg
$245.00
In stock
1404-100
100 mg
$895.00
In stock

Biotin-PEG4-NHS Ester is an amine-reactive, water-soluble labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers in aqueous media. The hydrophilic polyethylene glycol (PEG) spacer arm of this reagent imparts water solubility that is transferred to the labeled molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm also gives the reagent a long and flexible connection to minimize steric hindrance involved with binding to avidin molecules.

Biotin-PEG4-NHS Ester STP Ester undergoes hydrolysis in aqueous media at much slower rate compared to compared to DBCO-Sulfo Ester allowing for more efficient labeling of biomolecules in aqueous media.

Molecular weight
719.72
Chemical composition
C27H37F4N3O11S2
CAS
N/A
Solubility
DMSO, DMF, Water
Purity
>90%
Appearance
White to grey amorphous solid
Storage conditions
-20°C. Desiccate
Shipping conditions
Ambient temperature

Biotin-PEG4-NHS Ester is an amine-reactive, water-soluble labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers in aqueous media. The hydrophilic polyethylene glycol (PEG) spacer arm of this reagent imparts water solubility that is transferred to the labeled molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm also gives the reagent a long and flexible connection to minimize steric hindrance involved with binding to avidin molecules.

4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) esters is another type of carboxylic acid derivative that react with primary amines forming covalent amide bond. The amine linkage bond is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters. However, in most cases, STP ester displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers