Biotin-PEG4-Methyltetrazine

Catalog # Pkg Size Price(USD) Quantity
1024-100 100 mg $495.00
1024-25 25 mg $195.00
1024-10 10 mg $95.00

Methyltetrazine-activated biotinylation reagent that reacts with TCO-containing compounds via a Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1 s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.