Biotin Alkyne

Catalog#
Unit Size
Price (USD)
Availability
Qty
1266-5
5 mg
$79.00
In stock
1266-25
25 mg
$329.00
In stock
1266-100
100 mg
$1,095.00
In stock

    Biotin Alkyne (PEG4 carboxamide-Propargyl Biotin) is non-cleavable, alkyne-activated biotinylation reagent that can be reacted with azides via a copper-catalyzed click reaction to produce a stable triazole linkage. Biotin Alkyne is structurally identical to Biotin Alkyne (PEG4 carboxamide-Propargyl Biotin), catalog number: B10185, sold by ThermoFisher Scientific, and can be used as less expensive replacement.

    Molecular weight
    528.26
    Chemical composition
    C24H40N4O7S
    CAS
    N/A
    Solubility
    DMSO, DMF
    Purity
    >95% (HPLC)
    Appearance
    White to grey amorphous solid
    Storage conditions
    -20°C
    Shipping conditions
    Ambient temperature

    Biotin Alkyne (PEG4 carboxamide-Propargyl Biotin) is non-cleavable, alkyne-activated biotinylation reagent that can be reacted with azides via a copper-catalyzed click reaction to produce a stable triazole linkage. Biotin Alkyne allows for selective labeling of various azide-containing molecules (such as DNA, oligonucleotides, and proteins) with biotin for the subsequent detection or affinity purification with streptavidin, avidin or NeutrAvidin® biotin-binding protein.

    Biotin Alkyne is structurally identical to Biotin Alkyne (PEG4 carboxamide-Propargyl Biotin), catalog number: B10185, sold by ThermoFisher Scientific, and can be used as less expensive replacement.

    chemical structure

    1. Coates, H. W. et al. (2021). The mammalian cholesterol synthesis enzyme squalene monooxygenase is proteasomally truncated to a constitutively active form. J Biol Chem., Online ahead of print. [PubMed]
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