Azidoacetic Acid is a simple azido-containing building block that can be used to modify primary amines in the presence activators (e.g. EDC, or DCC) with azide (N3) group through a stable amide bond for subsequent ligation to terminal alkynes, strained cyclooctynes (e.g. DBCO or BCN compounds) or phosphine-labeled molecules. A short spacer arm adds minimal mass to modified molecules.
DMSO, DMF, DCM, THF, Chloroform
Colorless to slightly yellow oil
An amine-reactive, non-activated reagent with hydrophilic PEG4 spacer arm.
A water-soluble reagent for labeling antibodies, proteins and other molecules containing primary amines.
An amine-reactive labeling reagent with enhanced water stability and solubility.