Azido-PEG4-NHS Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
AZ103-25
25 mg
$79.00
In stock
AZ103-100
100 mg
$195.00
In stock
AZ103-1000
1000 mg
$525.00
In stock

    Azido-PEG4-NHS Ester is a labeling reagent that can be used to modify primary amine groups (e.g., a side chain of lysine residues or aminosilane-coated surfaces) with an azido group via a stable amide bond. The azide (N3) group reacts with terminal alkynes via CuAAC, strained cyclooctynes (e.g. DBCO or BCN compounds) via Cu-free click reaction or with phosphine-labeled molecules by a mechanism known as Staudinger chemistry, enabling efficient and specific conjugation of derivatized molecules in biological samples.

    Molecular weight
    388.37
    Chemical composition
    C15H24N4O8
    CAS
    944251-24-5
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    Colorless to slightly yellow oil
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Ambient temperature

    1. Hu, Y., Glazier, R., et al. (2021). DNA-based microparticle tension sensors (µTS) for measuring cell mechanics in non-planar geometries and for high-throughput quantification. Angew Chem Int Ed Engl., Online ahead of print. [PubMed]
    2. Bazrafshan, A. et al. (2021). DNA Gold Nanoparticle Motors Demonstrate Processive Motion with Bursts of Speed Up to 50 nm Per Second. ACS Publications, Online ahead of print. [PubMed]
    3. Bazrafshan, A., et al. (2020). Tunable DNA Origami Motors Translocate Ballistically Over μm Distances at nm/s Speeds. Angew. Chem. Int. Ed., 59(24), 9514-21. [PubMed]
    Related Products
    DBCO-PEG5-TFP Ester

    An amine-reactive reagents with enhanced labeling efficiency.

    DBCO-PEG5-NHS Ester

    An amine-reactive labeling reagent with enhanced water stability and solubility.