Alkyne Sphinganine

Catalog#
Unit Size
Price (USD)
Availability
Qty
1452-1
1 mg
$129.00
In stock
1452-5
5 mg
$395.00
In stock
1452-25
25 mg
$1,295.00
In stock

Alkyne Sphinganine a metabolic labeling reagent that contains a terminal alkyne moiety that allows for the subsequent tagging of protein−lipid complexes by click chemistry. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry’, in the presence of a copper (Cu)-containing catalyst allowing for the visualization and proteomic profiling of protein−sphingolipid complexes in living cells.

Molecular weight
297.46
Chemical composition
C18H35NO2
CAS
n/a
Solubility
DMSO, DMF
Purity
>95% (H NMR)
Appearance
White crystalline
Storage conditions
-20°C.
Shipping conditions
Ambient temperature

1. Gaebler A., et al. (2016). A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins. J. Lipid Res., 57, 1934-47. [PubMed]

2. Gaebler A., et al. (2013). Alkyne lipids as substrates for click chemistry-based in vitro enzymatic assays. J. Lipid Res., 54, 2282-90. [PubMed]

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