Alkyne-PEG4-NHS Ester

Catalog#
Unit Size
Price (USD)
Availability
Qty
TA103-25
25 mg
$139.00
In stock
TA103-100
100 mg
$265.00
In stock
TA103-1000
1000 mg
$870.00
In stock

    Alkyne-PEG4-NHS Ester is a labeling reagent that can be used to modify primary amine groups (e.g., a side chain of lysine residues or aminosilane-coated surfaces) with a terminal alkyne group via a stable, covalent amide bond. The terminal alkyne group can be reacted with azides via CuAAC enabling efficient and specific conjugation of derivatized molecules in biological samples.

    Molecular weight
    401.41
    Chemical composition
    C18H27NO9
    CAS
    1393330-40-9
    Solubility
    DMSO, DMF, DCM, THF, Chloroform
    Purity
    >95% (HPLC)
    Appearance
    Colorless to slightly yellow oil
    Storage conditions
    -20°C. Desiccate
    Shipping conditions
    Ambient temperature

    1. Graham, A. J., et al. (2022). Extracellular Electron Transfer Enables Cellular Control of Cu(I)-Catalyzed Alkyne-Azide Cycloaddition. ACS Cent Sci., 8 (2), 246-257. [PubMed]
    2. Hu, Y., Glazier, R., et al. (2021). DNA-based microparticle tension sensors (µTS) for measuring cell mechanics in non-planar geometries and for high-throughput quantification. Angew Chem Int Ed Engl., Online ahead of print. [PubMed]
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