6-Azide-Trehalose (6-TreAz)

Catalog#
Unit Size
Price (USD)
Availability
Qty
1472-5
5 mg
$129.00
In stock
1472-25
25 mg
$395.00
In stock
1472-100
100 mg
$895.00
In stock

Metabolic labeling with unnatural sugar substrates is a powerful alternative for investigating glycoconjugates in living organisms. Trehalose glycolipids can be metabolically labeled with 6-azide-modified trehalose (TreAz) analogues in live mycobacteria, enabling bioorthogonal ligation with alkyne-functionalized fluorescent probes. This strategy can be used for imaging glycolipid distribution, trafficking, and dynamics as well as metabolite profiling and discovery.

Molecular weight
367.31
Chemical composition
C12H21N3O10
CAS
n/a
Solubility
Water, DMSO, DMF
Purity
>90%
Appearance
White to grey amorphous solid
Storage conditions
-20°C.
Shipping conditions
Ambient temperature

1. Swarts, B.M., et al. (2012). Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry.J. Am. Chem. Soc., 134: 13123-6. [PubMed]

Related Products
AFDye 488 Alkyne

Excitation maximum: 494 nm
Emission maximum: 517 nm