6-Azide-Trehalose (6-TreAz)

Catalog#
Unit Size
Price (USD)
Availability
Qty
1472-5
5 mg
$179.00
In stock
1472-25
25 mg
$495.00
In stock
1472-100
100 mg
$1,095.00
In stock

    Metabolic labeling with unnatural sugar substrates is a powerful alternative for investigating glycoconjugates in living organisms. Trehalose glycolipids can be metabolically labeled with 6-azide-modified trehalose (TreAz) analogues in live mycobacteria, enabling bioorthogonal ligation with alkyne-functionalized fluorescent probes. This strategy can be used for imaging glycolipid distribution, trafficking, and dynamics as well as metabolite profiling and discovery.

    Molecular weight
    367.31
    Chemical composition
    C12H21N3O10
    CAS
    n/a
    Solubility
    Water, DMSO, DMF
    Purity
    >90%
    Appearance
    White to grey amorphous solid
    Storage conditions
    -20°C.
    Shipping conditions
    Ambient temperature

    1. Swarts, B.M., et al. (2012). Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry.J. Am. Chem. Soc., 134: 13123-6. [PubMed]
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