5-Ethynyl Uridine (5-EU)

Molecular Biology Grade

Catalog#
Unit Size
Price (USD)
Availability
Qty
1261-10
10 mg
$89.00
In stock
1261-25
25 mg
$205.00
In stock
1261-100
100 mg
$495.00
In stock
1261-500
500 mg
$1,195.00
In stock

    5-Ethynyl uridine (5-EU) is an alkyne-containing metabolic labeling reagent used to detect global RNA transcription temporally and spatially in both in-vitro and in-vivo with the modified nucleotide. The alkyne handler can be used for subsequent ligation to azide-containing molecules through a highly efficient click chemistry reaction.

    Molecular biology grade 5-Ethynyl Uridine is HPLC purified to achieve the highest purity possible.

    Molecular weight
    268.22
    Chemical composition
    C11H12N2O6
    CAS
    69075-42-9
    Solubility
    Water, DMSO, DMF
    Purity
    >95% (HPLC)
    Appearance
    Off white to grey crystalline
    Storage conditions
    -20°C.
    Shipping conditions
    Ambient temperature

    1. Morral, C., et al. (2020). Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer. Cell Stem Cell., 26 (6), 845-861.e12. [PubMed]
    2. Banerjee, A.K.,et al. (2020). SARS-CoV-2 disrupts splicing, translation, and protein trafficking to suppress host defenses. Cells., [doi: https://doi.org/10.1016/j.cell.2020.10.004]
    Related Products
    Biotin Azide

    An azide-activated biotinylation reagent.